Central odontogenic fibroma, its treatment and its recurrence. In this report, a 10yearold male patient is presented, who was diagnosed with central odontogenic fibroma of simple type from clinical, radiological, and histopathological findings. Calcifying epithelial odontogenic tumors and calcifying odontogenic cysts are rare, benign odontogenic tumors. Histopathologically, of is characterized by variable amounts of inactivelooking odontogenic. Differential diagnosis of radiolucent lesions in the molarpremolar region of mandible which involve impacted tooth may include central odontogenic fibroma, hyperplastic dental follicle, dentigerous. Central odontogenic fibroma of maxilla a case report. A case report ugo covani 1, roberto crespi 2, nicola perrini 3, antonio barone 2 1 associate professor and chairman of oral pathology and medicine school of dental medicine and nanoworld institute university of genova, italy. Odontogenic fibroma presents as a radiolucent image usually unilocular with well defined borders whereas in our case.
The central odontogenic fibroma cof is an extremely rare benign neoplasm of intraosseous or central presentation, being itself only 0. Largely unknown for sporadic ossifying fibroma can rarely show syndromic inherited association. Berlin, germany, springerverlag, 1992, p 11 combined central odontogenic fibroma and giant cell granulomalike lesion of the mandible. It is a lesion associated with the crown of an unerupted tooth resembling dentigerous cyst. A central odontogenic fibroma cof is a rare and benign tumor accounting for only 0. The lesion was diagnosed as a central odontogenic fibroma, an uncommon benign neoplasm derived from dental apparatus, and was removed by curettage. Clinically, of is most common in the mandibularpremolar region of female patients in the second to fourth decades of life and is frequently found as radiolucent lesions that may induce root resorption. The study also presents a oneyear period of postsurgical observation. The aim of this case report was to analyze clinical and histological features of a central odontogenic fibroma followed up for 6 years after surgical excision. The lesion appears both in the maxilla and mandible. Small central odontogenic fibroma mimicking hyperplastic. Central odontogenic fibroma is a rare odontogenic neoplasm that originates from odontogenic ectomesenchyme. Bearing in mind the rareness of the tumour, 8 new cases of central odontogenic fibroma have been found by analyzing the clinical. A case report ugo covani 1, roberto crespi 2, nicola perrini 3, antonio barone 2 1 associate professor and chairman of oral pathology and medicine school of dental medicine and nanoworld institute.
A case of peripheral odontogenic fibroma with its clinicopathologic findings are documented here. Ossifying odontogenic fibroma e589 case report a 43yearold woman with noncontributory medical, social, and cultural records was referred to the oral and. The who has defined cof as a rare neoplasm characterized by varying amounts of inactive looking odontogenic epithelium embedded in a mature, fibrous stroma. External tooth resorption associated with a peripheral odontogenic. It may evolve from the dental follicle, the dental papilla, or the periodontal membrane. Epithelium rich type central odontogenic fibroma in. Central odontogenic fibroma cof represents a rare group of benign.
It has also been reported that they commonly occur in association with an impacted tooth. Odontogenic fibrosarcoma definition of odontogenic. Pdf the combination of central odontogenic fibroma and central giant cell. Pdf central odontogenic fibroma cof represents a rare group of benign. History indicates that a variety of conditions had been reported as odontogenic fibroma. Central odontogenic fibroma has been defined as a benign odontogenic tumor, representing the intraosseous counterpart of a peripheral odontogenic fibroma. This appearance is most consistent with a benign odontogenic ossifying fibroma which can be followed. Central odontogenic fibroma cof is a rare tumor that accounts for 0. It has a diverse histopathology and a certain degree of controversy still exists regarding the diagnostic criteria. It appears to be far more common than its intraosseous counterpart, central odontogenic fibroma. The central odontogenic fibroma cof is a benign odontogenic tumour derived from the dental mesenchymal tissues. Giant odontogenic fibroma of maxilla brajendra baser 1, arvind kinger 1, geeti v mitra 2, manya thakur roy 1 1 department of ent, samc and pg institute, indore, madhya pradesh, india 2 department of oral and maxillofacial surgery, samc and pg institute, indore, madhya pradesh, india. Cemento ossifying fibroma is a benign, non odontogenic tumour of the jaw, a subdivision of. A central odontogenic fibroma cof is a rare tumor of odontogenic origin with a diverse histopathology found in both the mandible and the maxilla.
Pdf case report smj a rare case report of hybrid central. Giant odontogenic fibroma of maxilla baser b, kinger a, mitra. The study of odontogenic fibroma has been mentioned in research publications which can be found using our bioinformatics tool below. The patient remains asymptomatic after thirteen years of followup, which supports. Peripheral odontogenic fibroma is an uncommon benign tumour of the gum and is the equivalent of a central odontogenic fibroma occuring outside of bone. Cementoossifying fibroma is an unusual benign odontogenic tumor that is limited to the teeth bearing jaws and facial bones. Here, a case of central odontogenic fibroma in a 17yearold male is reported. Giant odontogenic fibroma of maxilla baser b, kinger a. Central odontogenic fibroma, its treatment and its. Central odontogenic fibroma cof is a rare, benign neoplasm of mesenchymal origin that makes up less than 5% of odontogenic tumors commonly found in women in ratio 2. Ithe present study outlines the case of a 30yearold patient with central odontogenic fibroma. These are slow growing, painless lesions which are seen more commonly in women between the third and fourth decades of life. Other odontogenic tumors such as the odontoma and the amyloid producing odontogenic tumor apot were not evaluated due to their relative very low incidence in dogs.
Concurrent central odontogenic fibroma and dentigerous cyst in the. Hybrid central odontogenic fibroma with giant cell granuloma like. Springerverlag, 1992, p 11 combined central odontogenic fibroma and giant cell granulomalike lesion of the mandible. Central odontogenic fibroma cof is an extremely rare benign tumor that accounts for 0. The who defines central odontogenic fibroma as fibroblastic neoplasm containing variable amounts of apparently inactive odontogenic epithelium and is classified as odontogenic tumor of ectomesenchyme with or without.
It has been defined as a benign neoplasm, which appears in the jaw. Asymptomatic or swelling and tooth mobility more common sites. Peripheral odontogenic fibroma is one of the most common of the rare. Different studies reported high variability in the incidence rate as being between 3 and 23% of all odontogenic tumors 2,3. Wikiproject dentistry rated stubclass, lowimportance this article is supported by wikiproject dentistry. Cirugia bucal oral surgery central odontogenic fibroma central odontogenic fibroma. Odontogenic fibroma, central ddmfr oral and maxillofacial. Who classification benign odontogenic epithelium without odontogenic ectomesenchyme ameloblastoma squamous odontogenic tumor pindborgs tumor clear cell odontogenic tumor odontogenic epithelium with odontogenic ectomesenchyme with or without dental hard tissue formation. Central odontogenic fibroma cof is a rare benign nonepithelial tumor arising from odontogenic mesenchymal tissues with reported incidence of only 0. They present as firm, smooth swellings of the gingiva and are normally indistinguishable from gingival hyperplasia. Peripheral odontogenic fibroma is often misdiagnosed as fibrous epulis and easily confused with peripheral osteofibroma. Central odontogenic fibroma current concepts gardner 1996. Disease bioinformatics research of odontogenic fibroma has been linked to fibroma, odontogenic tumors, neoplasms, mandibular neoplasms, gingival neoplasms. Combined central odontogenic fibroma and giant cell.
Central odontogenic fibroma cof is an uncommon benign neoplasm composed by varying amounts of inactivelooking odontogenic epithelium embedded in a neoplastic mature and fibrous stroma 112. Hyperparathyroidism jaw tumor syndrome head neck pathol 2014. Giant odontogenic fibroma of maxilla brajendra baser 1. According to site, as peripheral or central and histologically as poor type simple type and epithelium rich type complex or the who type. We report two cases of an exceptional combination of these tumors with either an ameloblastic fibroodontoma or an odontoma.
Odontogenic, tumors, fibroma, central introduction odontogenic fibroma odonf is a mesenchymal odontogenic tumor 1. Hybrid central odontogenic fibroma with giant cell granulomalike. Combined central odontogenic fibroma and giant cell granuloma. Apr 22, 2011 central odontogenic fibroma has been defined as a benign odontogenic tumor, representing the intraosseous counterpart of a peripheral odontogenic fibroma. Codf is defined as a fibroblastic neoplasm containing varying amounts of apparently inactive odontogenic epithelium. The lesion may evolve from a dental germ dental papilla or follicle or from the periodontal membrane, and therefore is invariably be related to the coronal or radicular portion of teeth. Central odontogenic fibroma codf is an extremely rare benign tumor accounting for 0.
The expansile and heterogenous feature of cemento ossifying fibroma often makes it resembles fibrous dysplasia. Histological features of peripheral odontogenic fibroma is cellular fibrous tissue. It must be distinguished from the more common peripheral ossifying fibroma. Histological features of peripheral odontogenic fibroma is. Central odontogenic fibroma of the maxilla a case report. A central odontogenic fibroma cof is a rare tumor of odontogenic origin with a diverse histopathology found in both the mandible and the. Odontogenic fibroma pdf the odontogenic fibroma is a rare, object oriented systems development ali bahrami free pdf dow benign tumor of mesodermal origin, and one of the most illdefined and least understood of all odontogenic neoplasms. Aarthinisha sree balaji dental college and hospital, bharath university, chennai, india abstract. In addition other benign tumour of bone, such as osteoblastoma. If you want to participate andor join, please visit the project page. The ratio of occurrence of the central to peripheral odontogenic fibroma is 1. Odontogenic tumors fibroma adult humans pathology diagnosis a b s t r a c t central odontogenic. Odontogenic fibroma of is a rare benign odontogenic neoplasm. Dec 01, 2015 odontogenic fibroma of, a rare odontogenic tumor of mesodermal origin, has been thought to originate from either dental follicle, periodontal ligament, or dental papilla 1.
It is a rare tumour and only 70 cases of it have been published. Immunohistochemical staining with pancytokeratin ck highlighted the odontogenic epithelial component merging with the gcg component. Central odontogenic fibroma cof is a relatively rare benign odontogenic neoplasm of jawbones. Odontogenic fibroma is a rare tumor, and the who has categorized it in two types. Differential diagnosis of radiolucent lesions in the molarpremolar region of mandible which involve impacted tooth may include central odontogenic fibroma, hyperplastic dental follicle. Odontogenic fibroma definition of odontogenic fibroma by. For many years there was considerable confusion concerning the criteria by which the lesion should be diagnosed and as a result, a verity of different conditions were being reported as odontogenic fibroma of. This report of odontogenic fibromas occurring in female patients 8 and 73 years of age contributes to the mounting evidence that this is a benign odontogenic tumor with distinctive clinical and microscopic features which differentiate it from the odontogenic myxoma and the desmoplastic fibroma of bone. The latter is a reactive lesion, derived from the periosteum and can produce osteoid and woven bone 14. A 46yearold female, demonstrated a multilocular, septated radiolucency below and. Odontogenic fibroma of, a rare odontogenic tumor of mesodermal origin, has been thought to originate from either dental follicle, periodontal ligament, or dental papilla 1. Introduction central odontogenic fibroma cof is a rare, benign, slowgrowing intraosseous odontogenic tumor, and accounts for 0. The tumour developed in the alveolar process of the maxilla in the area of 15. A rare case p balaji1, ashish gupta2, poornima govindraju3, vinitra vasan2, usha jambunath2 1professor, department of oral medicine and radiology, rajarajeswari dental college and hospital, bengaluru, karnataka, india.
It is a rare lesion that could be seen in all agegroups and that it is found both in the mandible and in the maxilla. It was previously known as a fibromatous epulis and ossifying epulis depending on the degree of mineralization. Histologically, all three lesions demonstrated a blend of odontogenic epithelial islands with numerous multinucleated giant cells in a highly. Since the present case showed a multilocular radiolucency with partially illdefined border between the right mandibular condyle and the distal root of the. Cemento ossifying fibroma is a benign, non odontogenic tumour of the jaw, a subdivision of fibroosseous lesions. Aug, 2010 an osteolytic tumour of the mandible with prominent expansive growth on the alveolar ridge and displacement of the involved teeth is described in a 28yearold man. The aim of this study was to describe the clinicopathologic and immunohistochemical characteristics of 14 cases of central odontogenic fibroma cof, and the ultrastructural features of 2 of them. Radiological findings consist of radiolucent areas with welldefined bony margins. Epithelium rich type central odontogenic fibroma in maxilla. Peripheral odontogenic fibroma is a benign, slowgrowing, exophytic lesion occurring on the gingiva. Peripheral odontogenic fibroma is a benign tumour that arises from the periodontal ligament. A case of central odontogenic fibroma cof of the epitheliumrich type granular cell variant is reported.
Central odontogenic fibroma a pediatric variant pavan p1, shyam prasad reddy d2, pavan g kulkarni3 abstract. Who classification benign odontogenic epithelium without odontogenic ectomesenchyme ameloblastoma squamous odontogenic tumor pindborgs tumor clear cell odontogenic tumor odontogenic epithelium with odontogenic ectomesenchyme with or without dental hard tissue. Central odontogenic fibroma a report of a quiet and. Additionally, a manual search of relevant textbooks,1, 15, 16 and. The study describes the clinical symptoms, the radiological image, treatment method and histopathological image of the tumour.
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